{"id":546,"date":"2026-07-27T16:11:44","date_gmt":"2026-07-27T16:11:44","guid":{"rendered":"https:\/\/anmarcs.calmo.es\/securite\/"},"modified":"2026-07-29T14:34:25","modified_gmt":"2026-07-29T14:34:25","slug":"securite","status":"publish","type":"page","link":"https:\/\/anmarcs.es\/fr\/securite\/","title":{"rendered":"S\u00e9curit\u00e9"},"content":{"rendered":"\t\t
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S\u00e9curit\u00e9<\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Nous \u00e9valuons la tol\u00e9rance et la compatibilit\u00e9 des produits cosm\u00e9tiques au moyen de tests tels que le Patch Test, l\u2019Open Test, le HRIPT et le Test d\u2019Usage.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Contr\u00f4le sp\u00e9cialis\u00e9<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u00c9tudes de s\u00e9curit\u00e9 cosm\u00e9tique<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Chez ANMAR Clinical Services<\/strong> nous r\u00e9alisons des \u00e9tudes de s\u00e9curit\u00e9 sur des volontaires sains<\/strong> afin d\u2019\u00e9valuer la compatibilit\u00e9, la tol\u00e9rance et le profil de s\u00e9curit\u00e9 des produits cosm\u00e9tiques. Ces \u00e9tudes permettent d\u2019observer la r\u00e9ponse de la peau ou des muqueuses<\/strong> \u00e0 l\u2019application d\u2019un produit, ainsi que de v\u00e9rifier d\u2019\u00e9ventuelles r\u00e9actions imm\u00e9diates, retard\u00e9es, r\u00e9p\u00e9titives ou \u00e0 long terme. Les \u00e9tudes sont r\u00e9alis\u00e9es sous le contr\u00f4le sp\u00e9cialis\u00e9<\/strong> requis dans chaque cas : dermatologique, ophtalmologique, p\u00e9diatrique, odontologique ou gyn\u00e9cologique, selon le type de produit, sa zone d\u2019application et l\u2019objectif de l\u2019essai.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Les volontaires<\/strong> sains participant \u00e0 ces tests<\/strong> sont s\u00e9lectionn\u00e9s selon diff\u00e9rents crit\u00e8res<\/strong>, tels que la qualit\u00e9 de la peau \u2014 normale, sensible ou extr\u00eamement sensible \u2014, le sexe \u2014 femmes ou hommes \u2014 ou l\u2019\u00e2ge \u2014 peaux jeunes, matures ou enfants \u2014.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\u00c9valuation des produits cosm\u00e9tiques<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Types d\u2019\u00e9tudes<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Parmi les \u00e9tudes de s\u00e9curit\u00e9 les plus fr\u00e9quentes figurent le Patch Test<\/strong> simple unique, l\u2019Open Test<\/strong>, l\u2019\u00e9tude du potentiel sensibilisant et allerg\u00e9nique HRPT ou HRIPT<\/strong>, ainsi que les essais de compatibilit\u00e9 cutan\u00e9e \u00e0 long terme, \u00e9galement appel\u00e9s Tests d\u2019Usage<\/strong> en conditions normales.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Patch test <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/i><\/span>\n\t\t\t<\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Le Patch Test<\/strong> est une \u00e9tude de compatibilit\u00e9 cutan\u00e9e<\/strong> qui permet de confirmer les donn\u00e9es obtenues pr\u00e9alablement au moyen d\u2019essais in vitro.<\/p>\n

Il consiste \u00e0 appliquer le produit cosm\u00e9tique sur le dos du volontaire sous occlusion, c\u2019est-\u00e0-dire \u00e0 l\u2019aide d\u2019un patch<\/strong>. Un second patch est \u00e9galement plac\u00e9 afin d\u2019\u00e9carter la possibilit\u00e9 qu\u2019une r\u00e9action soit due au patch lui-m\u00eame et non au produit \u00e9valu\u00e9.<\/p>\n

Le patch reste en contact avec la peau pendant 48 heures<\/strong>. Pass\u00e9 ce d\u00e9lai, il est retir\u00e9 en pr\u00e9sence d\u2019un dermatologue et, 30 minutes plus tard, l\u2019aspect de la peau est \u00e9valu\u00e9<\/strong>. Lors de cette \u00e9valuation, on observe l\u2019\u00e9ventuelle apparition de signes tels qu\u2019un \u00e9ryth\u00e8me, un \u0153d\u00e8me, des papules, des v\u00e9sicules, des bulles, des pustules, une r\u00e9flectivit\u00e9, une s\u00e9cheresse, une desquamation ou un effet d\u00e9tergent. Ce type d\u2019\u00e9tude permet d\u2019\u00e9valuer la compatibilit\u00e9 cutan\u00e9e du produit et de v\u00e9rifier si son application provoque une r\u00e9action observable dans la zone \u00e9valu\u00e9e.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Open test <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/i><\/span>\n\t\t\t<\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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L\u2019Open Test<\/strong> est r\u00e9alis\u00e9 lorsque, en raison de la sp\u00e9cificit\u00e9 du produit, il n\u2019est pas possible d\u2019effectuer un test sous occlusion tel que le Patch Test.<\/p>\n

Le test consiste en une application unique ou r\u00e9p\u00e9t\u00e9e du produit \u00e9tudi\u00e9<\/strong>. Selon le type de produit, l\u2019application peut \u00eatre effectu\u00e9e sur la face interne de l\u2019avant-bras<\/strong>, dans le cas de la compatibilit\u00e9 dermatologique, ou autour de la muqueuse oculaire, sur la muqueuse buccale ou sur la zone intime externe. Apr\u00e8s l\u2019application, la r\u00e9ponse de la peau<\/strong> ou des muqueuses est observ\u00e9e au bout de 30 minutes, d\u2019une heure, ainsi qu\u2019\u00e0 24 et 48 heures.<\/p>\n

L\u2019Open Test permet d\u2019identifier les r\u00e9actions d\u2019irritation<\/strong> observables \u00e0 l\u2019\u0153il nu, appel\u00e9es signes cliniques<\/strong>. De plus, un examen macroscopique est r\u00e9alis\u00e9 selon une \u00e9chelle num\u00e9rique \u00e9tablie, les sensations d\u2019inconfort d\u00e9crites par les volontaires sont recueillies et, lorsque cela est justifi\u00e9, les manifestations pouvant appara\u00eetre dans une zone t\u00e9moin sont \u00e9galement \u00e9valu\u00e9es.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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HRPT \/ HRIPT <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/i><\/span>\n\t\t\t<\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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L\u2019\u00e9tude du potentiel sensibilisant et allerg\u00e9nique<\/strong>, connue sous le nom de HRPT ou HRIPT<\/strong>, est r\u00e9alis\u00e9e au moyen d\u2019applications r\u00e9p\u00e9t\u00e9es sous occlusion<\/strong>. Ce type d\u2019\u00e9tude permet d\u2019\u00e9valuer la possible r\u00e9ponse sensibilisante ou allerg\u00e9nique<\/strong> du produit cosm\u00e9tique chez des volontaires sains, selon un protocole sp\u00e9cifique<\/strong> et sous contr\u00f4le sp\u00e9cialis\u00e9.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Test d\u2019Usage <\/div><\/span>\n\t\t\t\t\t\t\t\n\t\t\t<\/i><\/span>\n\t\t\t<\/i><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t
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Le Test d\u2019Usage<\/strong>, \u00e9galement appel\u00e9 Test d\u2019Acceptabilit\u00e9<\/strong>, permet d\u2019\u00e9valuer le comportement du produit dans des conditions normales d\u2019utilisation<\/strong>. Il peut \u00eatre r\u00e9alis\u00e9 sous contr\u00f4le dermatologique, avec des sujets examin\u00e9s individuellement par un investigateur dermatologue, ou sous contr\u00f4le p\u00e9diatrique, gyn\u00e9cologique, ophtalmologique ou odontologique, selon le type de produit et sa zone d\u2019application.<\/p>\n

Cette \u00e9tude permet de v\u00e9rifier l\u2019absence de r\u00e9actions d\u2019inconfort et d\u2019irritations cumulatives<\/strong>, aussi bien fonctionnelles que physiques, associ\u00e9es \u00e0 l\u2019application du produit pendant une p\u00e9riode de 2 \u00e0 4 semaines. Les participants doivent r\u00e9pondre \u00e0 des crit\u00e8res d\u2019inclusion sp\u00e9cifiques<\/strong> et utiliser le produit dans des conditions normales.<\/p>\n

Le Test d\u2019Usage est r\u00e9alis\u00e9 apr\u00e8s le Patch Test, lorsque les r\u00e9sultats sont n\u00e9gatifs (produit non irritant) ou lorsqu\u2019il existe une r\u00e9action positive faible (produit l\u00e9g\u00e8rement irritant). Dans ces cas, le Test d\u2019Usage aide \u00e0 confirmer la signification clinique du Patch Test pr\u00e9alable.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"\"\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

S\u00e9curit\u00e9 Nous \u00e9valuons la tol\u00e9rance et la compatibilit\u00e9 des produits cosm\u00e9tiques au moyen de tests tels que le Patch Test, l\u2019Open Test, le HRIPT et le Test d\u2019Usage. Contr\u00f4le sp\u00e9cialis\u00e9 \u00c9tudes de s\u00e9curit\u00e9 cosm\u00e9tique Chez ANMAR Clinical Services nous r\u00e9alisons des \u00e9tudes de s\u00e9curit\u00e9 sur des volontaires sains afin d\u2019\u00e9valuer la compatibilit\u00e9, la tol\u00e9rance et […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"nxt-post-page-sidebar":"","nxt-post-page-display-sidebar":"","nxt-post-page-custom-sidebar":"","footnotes":""},"class_list":["post-546","page","type-page","status-publish","hentry"],"yoast_head":"\nS\u00e9curit\u00e9 - ANMAR Clinical Services<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/anmarcs.es\/seguridad\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"S\u00e9curit\u00e9 - ANMAR Clinical Services\" \/>\n<meta property=\"og:description\" content=\"S\u00e9curit\u00e9 Nous \u00e9valuons la tol\u00e9rance et la compatibilit\u00e9 des produits cosm\u00e9tiques au moyen de tests tels que le Patch Test, l\u2019Open Test, le HRIPT et le Test d\u2019Usage. Contr\u00f4le sp\u00e9cialis\u00e9 \u00c9tudes de s\u00e9curit\u00e9 cosm\u00e9tique Chez ANMAR Clinical Services nous r\u00e9alisons des \u00e9tudes de s\u00e9curit\u00e9 sur des volontaires sains afin d\u2019\u00e9valuer la compatibilit\u00e9, la tol\u00e9rance et […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/anmarcs.es\/seguridad\/\" \/>\n<meta property=\"og:site_name\" content=\"ANMAR Clinical Services\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-29T14:34:25+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/anmarcs.es\/wp-content\/uploads\/2026\/07\/Anmar-Seguridad-Tipos-01.webp\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/\",\"url\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/\",\"name\":\"S\u00e9curit\u00e9 - ANMAR Clinical Services\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/anmarcs.es\\\/wp-content\\\/uploads\\\/2026\\\/07\\\/Anmar-Seguridad-Tipos-01.webp\",\"datePublished\":\"2026-07-27T16:11:44+00:00\",\"dateModified\":\"2026-07-29T14:34:25+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/#primaryimage\",\"url\":\"https:\\\/\\\/anmarcs.es\\\/wp-content\\\/uploads\\\/2026\\\/07\\\/Anmar-Seguridad-Tipos-01.webp\",\"contentUrl\":\"https:\\\/\\\/anmarcs.es\\\/wp-content\\\/uploads\\\/2026\\\/07\\\/Anmar-Seguridad-Tipos-01.webp\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/seguridad\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\\\/\\\/anmarcs.es\\\/fr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"S\u00e9curit\u00e9\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#website\",\"url\":\"https:\\\/\\\/anmarcs.es\\\/\",\"name\":\"ANMAR Clinical Services\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/anmarcs.es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#organization\",\"name\":\"ANMAR Clinical Services\",\"url\":\"https:\\\/\\\/anmarcs.es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/anmarcs.es\\\/wp-content\\\/uploads\\\/2026\\\/07\\\/42949562f1b41ac7b0e1a8b948dce4c7.svg\",\"contentUrl\":\"https:\\\/\\\/anmarcs.es\\\/wp-content\\\/uploads\\\/2026\\\/07\\\/42949562f1b41ac7b0e1a8b948dce4c7.svg\",\"width\":162,\"height\":32,\"caption\":\"ANMAR Clinical Services\"},\"image\":{\"@id\":\"https:\\\/\\\/anmarcs.es\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"S\u00e9curit\u00e9 - ANMAR Clinical Services","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/anmarcs.es\/seguridad\/","og_locale":"fr_FR","og_type":"article","og_title":"S\u00e9curit\u00e9 - ANMAR Clinical Services","og_description":"S\u00e9curit\u00e9 Nous \u00e9valuons la tol\u00e9rance et la compatibilit\u00e9 des produits cosm\u00e9tiques au moyen de tests tels que le Patch Test, l\u2019Open Test, le HRIPT et le Test d\u2019Usage. 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